This is hard for me. My family has a lot of Alzheimers in it, I have had cancer issues in the past, I have vision issues, etc. I don't know what to choose if I had to choose just one. The one thing that makes me the saddest though is pediatric cancers and pediatric leukemia. I get so mad and frustrated when I see innocent kids have to go through so much pain and suffering for no reason. So if there could be one scientific or medical breakthrough I would like them to find a painless cure for all pediatric cancers and leukemia.